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Professional paper

THE ROLE OF IgG AVIDITY IN DIAGNOSTICS OF CYTOMEGALOVIRUS INFECTION DURING PREGNANCY

Nataša Beader ; Klinički bolnički centar u Zagrebu; Klinički zavod za kliničku i molekularnu mikrobiologiju, Kišpatićeva 12, 10 000 Zagreb
Snježana Škrablin-Kučić ; Odjel za patologiju trudnoće, Klinika za ženske bolesti i porode
Slobodan Mihaljević ; Odjel za anesteziologiju i intenzivno liječenje
Zoran Veir ; Klinika za kirurgiju, KBC zagreb

Fulltext: croatian, pdf (136 KB) pages 151-155 downloads: 4.921* cite
APA 6th Edition
Beader, N., Škrablin-Kučić, S., Mihaljević, S. & Veir, Z. (2009). ULOGA IgG AVIDNOSTI U DIJAGNOSTICI CITOMEGALOVIRUSNE INFEKCIJE TIJEKOM TRUDNOĆE. Gynaecologia et perinatologia, 18 (3), 151-155. Retrieved from https://hrcak.srce.hr/65960
MLA 8th Edition
Beader, Nataša, et al. "ULOGA IgG AVIDNOSTI U DIJAGNOSTICI CITOMEGALOVIRUSNE INFEKCIJE TIJEKOM TRUDNOĆE." Gynaecologia et perinatologia, vol. 18, no. 3, 2009, pp. 151-155. https://hrcak.srce.hr/65960. Accessed 23 Jul. 2021.
Chicago 17th Edition
Beader, Nataša, Snježana Škrablin-Kučić, Slobodan Mihaljević and Zoran Veir. "ULOGA IgG AVIDNOSTI U DIJAGNOSTICI CITOMEGALOVIRUSNE INFEKCIJE TIJEKOM TRUDNOĆE." Gynaecologia et perinatologia 18, no. 3 (2009): 151-155. https://hrcak.srce.hr/65960
Harvard
Beader, N., et al. (2009). 'ULOGA IgG AVIDNOSTI U DIJAGNOSTICI CITOMEGALOVIRUSNE INFEKCIJE TIJEKOM TRUDNOĆE', Gynaecologia et perinatologia, 18(3), pp. 151-155. Available at: https://hrcak.srce.hr/65960 (Accessed 23 July 2021)
Vancouver
Beader N, Škrablin-Kučić S, Mihaljević S, Veir Z. ULOGA IgG AVIDNOSTI U DIJAGNOSTICI CITOMEGALOVIRUSNE INFEKCIJE TIJEKOM TRUDNOĆE. Gynaecologia et perinatologia [Internet]. 2009 [cited 2021 July 23];18(3):151-155. Available from: https://hrcak.srce.hr/65960
IEEE
N. Beader, S. Škrablin-Kučić, S. Mihaljević and Z. Veir, "ULOGA IgG AVIDNOSTI U DIJAGNOSTICI CITOMEGALOVIRUSNE INFEKCIJE TIJEKOM TRUDNOĆE", Gynaecologia et perinatologia, vol.18, no. 3, pp. 151-155, 2009. [Online]. Available: https://hrcak.srce.hr/65960. [Accessed: 23 July 2021]

Abstracts
. Objective. Cytomegalovirus (CMV) is one of the leading causes of mental retardation and other neurological defects in infants. To date, there is no commonly accepted algorithm for detection of intrauterine HCMV infections during pregnancy and neonatal period. Primary CMV infections during gestation present a 40% risk of intrauterine transmission in contrast to nonprimary infections. In this small study, we decided to identify pregnant women with primary CMV infection with IgG avidity test. Material and methods. The study included 33 pregnant women whose sera were tested to CMV IgM, IgG antibodies and IgG avidity. All the blood samples were tested with antigenemia CMV pp65 test. Results. 3 (9%) pregnant women were CMV seronegative and 30 (91%) were CMV seropositive. Low IgG avidity index (AI) was detected in 1 (3%), intermediate in 3 (9%) and high AI in 26 (79%) pregnant women. CMV IgM antibodies with intermediate IgG AI were detected in 5 (15%) pregnant women. All the blood samples tested with antigenemia CMV pp65 test were negative. Conclusion. IgG avidity test differentiates primary from nonprimary CMV infection in pregnant women.

Keywords
cytomegalovirus; pregnancy; intrauterine infections; CMV IgG avidity

Hrčak ID: 65960

URI
https://hrcak.srce.hr/65960

[croatian]

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