Izvorni znanstveni članak

https://doi.org/10.2478/v10007-011-0018-2

Sinteza, antibakterijsko i potencijalno anti-HIV djelovanje nekoliko novih analoga imidazola

SWASTIKA GANGULY orcid.org/0000-0001-5042-0773 ; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India
VATSAL VIJAY VITHLANI ; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India
ANUP KUMAR KESHARWANI ; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India
RITU KUHU ; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India
LAKSHMANAN BASKAR ; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India
PAPIYA MITRAMAZUMDER ; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India
ASHOK SHARON ; Department of Applied Chemistry, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India
ABHIMANYU DEV ; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India

Sažetak

Sintetizirana je serija 1-(2-metil-4-nitro-imidazol-1-il)-3-arilamino-propan-2-ona (2a-e), 2-metil-5-nitro-1-{2-[arilmetoksi]etil}-1H- imidazola (5a-d) i N-(3-hidroksifenil)-2-(supstituiranih imidazol-1-il)alkanamida (8a-e) s ciljem dobivanja novih derivata imidazola sa širokim kemoterapijskim svojstvima. Navedeni spojevi ispitani su na anti-HIV i antibakterijsko djelovanje.

Ključne riječi

imidazol; reverzna transkriptaza; nenukleozidna reverzna transkriptaza; anti-HIV; antibakterijski

Hrčak ID:

66189

URI

https://hrcak.srce.hr/66189

Datum izdavanja:

1.6.2011.

Podaci na drugim jezicima: engleski

Posjeta: 2.188 *