Podocytes and the actin cytoskeleton as a feasible therapeutic target
DOI:
https://doi.org/10.18054/pb.v118i4.4576Abstract
Podocyte injury is a hallmark of the glomerular disease, which is a direct cause of chronic kidney diseases. Importantly, podocyte injury is a consequence of the dysregulation of the actin cytoskeleton. In diverse animal models of proteinuric glomerular disease, recovering the integrity of the actin structure in podocytes resulted in beneficial effects. In this review, we focus on the premise of targeting the actin cytoskeleton as a feasible therapeutics for treating chronic kidney diseasesDownloads
Published
2017-03-17
Issue
Section
Articles
License
The contents of PERIODICUM BIOLOGORUM may be reproduced without permission provided that credit is given to the journal. It is the author’s responsibility to obtain permission to reproduce illustrations, tables, etc. from other publications.