PKA and the Structural Kinome

Authors

  • Susan S. Taylor Department of Pharmacology and Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, CA 92093
  • Alexandr P. Kornev Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093

DOI:

https://doi.org/10.18054/pb.v118i4.4846

Abstract

In recognition of the first protein kinase structure that was solved 25 years ago, we review the history of the Structural Kinome. What did we learn prior to that first structure of the PKA catalytic subunit, what have we learned since the structure was solved, and what are our remaining challenges for the future?

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Published

2017-03-17

Issue

Vol. 118 No. 4 (2016)

Section

Articles

License

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