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Circumscribed Palmar Hypokeratosis – The First Case from South-East Europe
Branislav Lekić
; Clinic of Dermatovenereology Clinical Center of Serbia Belgrade Serbia
Biljana Janković
; Clinic of Dermatovenereology Clinical Center of Serbia Belgrade Serbia
Miloš Nikolić
; Department of Dermatovenereology Faculty of Medicine, University of Belgrade; Clinic of Dermatovenereology Clinical Center of Serbia Pasterova 2 11000 Belgrade Serbia
Abstract
Circumscribed palmar or plantar hypokeratosis (CPH) is a rare epidermal malformation, usually asymptomatic, consisting of a well-demarcated erythema with central depression and hyperkeratotic border which divides it from the normal skin. We report a 77-year-old woman with characteristic lesion of circumscribed palmar hypokeratosis on the right palm. Clinically, the lesion simulated porokeratosis of Mibelli, but histologically there was no cornoid lamella, while the characteristic depression of epidermis, with sharp stair in stratum corneum between the normal and involved skin was present. This is the first case of CPH diagnosed in the south-east of Europe. After a 9-year follow-up period and various treatment modalities, we confirmed the resistance of CPH. Since malignant transformation has been documented, a careful follow-up is to be recommended.
Keywords
Hrčak ID:
101618
URI
Publication date:
10.5.2013.
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