Original scientific paper
https://doi.org/10.5599/jese.2013.0030
Novel Mannich bases bearing pyrazolone moiety. Synthesis, characterization and electrochemical studies
Krishna Naik
; Sri Krishnadevaraya University, Anantapur, A.P., India
Aluru R. G. Prasad
; ICFAI Foundation for Higher Education, Hyderabad, A.P., India
Yadati N. Spoorthy
; Sri Krishnadevaraya University, Anantapur, A.P., India
Lakshmana R. K. R. Ravindranath
; Sri Krishnadevaraya University, Anantapur, A.P., India
Abstract
The present investigation describes a series of new {4-[3-Methyl-5-oxo-4-(4|-substituted phenyl hydrazono)-4,5-dihydro-pyrazol-1-yl]-phenoxy}-acetic acid (2-oxo-1-piperidine-1-ylmethyl-1,2-dihydro–indol-3-ylidene)-hydrazides synthesized by the Mannich reaction of {4-[3-Methyl-5-oxo-4-(4|-substituted phenyl hydrazono)-4,5-dihydro-pyrazol-1-yl]-phenoxy}-acetic acid (2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide with aqueous formaldehyde and a solution of piperidine in dimethylformamide. These novel Mannich bases were characterized by elemental analysis, IR, 1H NMR and mass spectral data. Electrochemical behavior of these compounds were studied by two techniques namely polarography and cyclic voltammetry. The results from both the techniques were compared and the reduction mechanism in acidic as well as basic medium was proposed.
Keywords
Mannich bases; synthesis; polarography; cyclic voltammetry; comparison; reduction mechanism
Hrčak ID:
103163
URI
Publication date:
19.4.2013.
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