Reumatizam, Vol. 57 No. 2, 2010.
Conference paper
Digital ulcers in systemic sclerosis
Višnja Prus
; Clinical Department for Immunology and Allergology, Clinic for Internal Medicine, Clinical Hospital Osijek, Osijek, Croatia
Abstract
Digital ulcers occur in up to 50% of patients with limited or diffuse systemic sclerosis. The lesions are extremely painful leading to substantial functional disability, local infection susceptibility and can escalate to gangrene and amputation. Underlying vasculopathy and angiopathy cause obliteration of digital arteries and ischemic tissue changes. Management of digital ulcers includes non-pharmacological and pharmacological modalities. Early diagnosis in preclinical phase would enable preventive treatment prior to irreversible changes.
Keywords
digital ulcers; systemic sclerosis; Raynaud phenomenon
Hrčak ID:
124636
URI
Publication date:
14.10.2010.
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