Reumatizam, Vol. 54 No. 1, 2007.
Professional paper
Proposal of Croatian Society for Rheumatology for anti-TNF-α therapy in adult patients with spondyloarthritides
Đurđica Babić-Naglić
; Clinic for Rheumatic Diseases and Rehabilitation of the School of Medicine, University of Zagreb, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Nadica Laktašić
; Clinic for Rheumatic Diseases and Rehabilitation of the School of Medicine, University of Zagreb, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Zrinka Jajić
; Clinic for Rheumatology, Physical Medicine and Rehabilitation, Clinical Hospital “Sestre milosrdnice”, Zagreb, Croatia
Branimir Anić
; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Jadranka Morović-Vergles
; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital “Dubrava”, Zagreb, Croatia
Božidar Ćurković
; Clinic for Rheumatic Diseases and Rehabilitation of the School of Medicine, University of Zagreb, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Abstract
Spondyloarthritides (SpA) as a group are one of the most common rheumatic disorders with a predominant affection of the spine. Conventinal disease modifying antirheumatic drugs which are effective in rheumatoid arthritis have poor effect on spinal inflammation. Today there
is confirmed efficacy of biologics in spondylitis. This therapy is expensive and potentially hazaradous. Croatian Society for Rheumatology set up recommendations for the use of TNF-α blockers in SpA. There are several important points to be considered before their use: diagnosis of Spa, duration and disease activity, previous therapy and it’s efficacy, application and efficacy of biologics,
contraindications and safety preacutions and finally a decision for continuous tretament with biologics.
Keywords
spondyloarthritides; anti-TNF-α therapy; recomendations
Hrčak ID:
125392
URI
Publication date:
1.7.2007.
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