Pregledni rad
INFLUENCE OF LEPTIN ON HORMONAL REGULATION SOWS' REPRODUCTIVE SYSTEM
Kristina Budimir
; Poljoprivredni fakultet Sveučilišta u Osijeku, Osijek, Hrvatska
Marcela Šperanda
; Poljoprivredni fakultet Sveučilišta u Osijeku, Osijek, Hrvatska
Sažetak
Leptin is a gene product of Lep gene which is responsible for causing obesity in domestic animals. It is a hormone which is synthesized in adipocytes and signaly to the body about available amounts of energy and in that way he affects the growth, development, reproduction, and metabolism. It is metabolic signal directly associated with the reproductive system. The amount of leptin and synthesized triglycerides stored in fatty tissue are increasing by the animals aging. It serves as the signal to the brain which will send information about reducing food intake and increasing energy consumption of the body. In the case of uniform consumption of energy proportion of leptin is equal to the amount of stored triglycerides in fatty tissue. The action of leptin in the hypothalamus is reflected in the control of food intake, thermogenesis and regulation of expression and secretion of neurotransmitters, neuropeptides and hormones of the hypothalamus, which include gonadotrophic releasing hormone (GnRH), galanin (GAL), neuropeptide Y, releasing growth hormone, somatostatin, thyroid releasing hormone and corticotropin releasing hormone. Its activity expressed through a leptin receptor that belongs to the cytokine family of receptors.The discovery of leptin has enabled a better understanding of the correlation between function of adipose tissue and the maintenance of homeostasis in pigs. Except leptin impact on the hypothalamic-pituitary-gonadal axis have other mediators such as glucose and insulin, free fatty acids and adrenal hormones. The aim of this paper is to provide insight on the impact of leptin on hormonal status of reproductive system sows.
Ključne riječi
leptin; hypothalamus; hormones; reproductive system of the sow
Hrčak ID:
138659
URI
Datum izdavanja:
2.4.2015.
Posjeta: 1.709 *