Izvorni znanstveni članak

https://doi.org/10.5562/cca2637

Incredible Role of Glycerol in Multicomponent Synthesis of 2,3-Dihydroquinazoline-4(1H)-ones and 1-Amidoalkyl-2-naphthols

Maryam Hajjami ; Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran
Fariba Bakhti ; Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran
Elahe Ghiasbeygi ; Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran

Sažetak

An efficient and green synthesis of 1-amidoalkyl-2-naphthols via one-pot three-component condensation of aromatic aldehydes, acetamide and 2-naphthol in the presence of catalytic amounts of glycerosulfonic acid in glycerol as a green solvent was elaborated. Also a simple method for the one-pot three-component synthesis of 2,3-dihydroquinazoline-4(1H)-ones using of isatoic anhydride, aldehydes and ammonium acetate in the presence of glycerol as a green catalyst and solvent was described. In this light we introduced the brilliant and valuable role of glycerol in the synthesis of 2,3-dihydroquinazoline-4(1H)-ones and 1-amidoalkyl-2-naphthols.

Ključne riječi

1-amidoalkyl-2-naphthol; glycerol; glycerosulfonic acid; multicomponent reaction; 2,3-dihydroquinazoline-4(1H)-ones; one-pot; catalyst

Hrčak ID:

141993

URI

https://hrcak.srce.hr/141993

Datum izdavanja:

20.7.2015.

Posjeta: 2.818 *