Short communication, Note
Cutaneous reactivity to grass pollen and house dust mite in prick test with two types of allergen extracts
J. Godnić-Cvar
; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska
B. Kanceljak-Macan
; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska
Abstract
The reliability of prick testing with allergen preparations produced in Yugoslavia was assessed by comparison to the internationally accepted ones (Pharmacia Diagnostica) of 100 000 BU activity. The following allergens were used: the mite Dermatophagoides pteronyssinus in 107 subjects, and grass pollens: Dactylis glomerata, Poa pratensis, Pbleum pratense and Secale cereale in 39 subjects. The clinical significance of the response was assessed in relation to the skin reaction to the negative control solution and positive histamine control (in concentration of 1 mg/ml). The results indicate that the allergen extract of Dermatophagoides pteronyssinus (3000 PNU/ml) produced in Yugoslavia does not provoke skin reactions comparable to those provoked by the standardized extract of 100 000 BU in contrast to the grass pollen allergens, with the exception of Poa pratensis, which evokes equivalent skin reactions. Thus grass pollen allergens are reliable extracts and can be applied with good confidence in routine work. The need to set more rigorous criteria for assessing skin prick reactions, when domestic, unstandardized products are used, emerged as a result of this study.
Keywords
Hrčak ID:
152231
URI
Publication date:
26.3.1990.
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