Short communication, Note

Cerebral glycolysis and glycogenolysis in diazinon treated animals

K. Husain ; Industrial Toxicology Research Centre, Lucknow, India
M.A. Matin ; Industrial Toxicology Research Centre, Lucknow, India

Abstract

Treatment with diazinon (40 mg/kg, i. p.) resulted in depletion of glycogen and increased activities of glycogen phosphorylase, phosphoglucomutase, hexokinase and lactate dehydrogenase in the brain of rats. The activity of glucose-o-phosphatase was not significantly changed. The level of lactic acid in the blood was raised, while that of pyruvic was not altered. The induced changes may be due to a compensatory mechanism providing extra energy on account of stimulatory effects in diazinon treated animals.

Keywords

Hrčak ID:

153946

URI

https://hrcak.srce.hr/153946

Publication date:

23.12.1986.

Article data in other languages: croatian

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