Acta clinica Croatica, Vol. 39 No. 4, 2000.
Izlaganje sa skupa
Age and Hemorheologic Changes in Stroke
Piotr Kowal
Grazyna Hurla
Sažetak
Stroke is known to be most common in the elderly. Rheologic factors play an important role in the cerebral flow regulation and distinctly correlate with the atherosclerotic process. The aim of this study was to assess the degree to which rheologic changes were related to the age of patients with acute cerebral ischemia. The study included 26 patients and 12 control subjects. Patients were divided into two age groups: 370 (n=11, mean age 77.8) and L60 (n=15, mean age 52.3) years. The following hemorheologic parameters were observed: blood viscosity (BV), plasma viscosity (PV), hematocrit (Htc), red cell deformability (RCD), internal erythrocyte viscosity (IEV), red cell aggregation (RCA), and fibrinogen concentration. Hemorheologic factors were estimated during the first 48 hours and after 3 weeks of disease onset. BV, PV, RCA, IEV and fibrinogen were significantly elevated, whereas Htc and RCD were significantly decreased in the 370-year group as compared with control subjects. Relative to the L60-year group, patients from the 370-year group showed significantly higher values of BV, PV, IEV and RCA, and significantly lower values of RCD and Htc. The hemorheologic profile at 3 weeks from stroke onset was similar to that recorded in the acute phase. Results of the study indicated that hemorheologic changes in patients with cerebral ischemia were clearly dependent on the patient age.
Ključne riječi
Cerebrovascular disorders, blood; Cerebrovascular accident, blood; Hemorheology; Age factors; Aged
Hrčak ID:
14986
URI
Datum izdavanja:
1.12.2000.
Posjeta: 1.910 *