Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2016.57.42
Shear-wave sonoelastographic features of invasive lobular breast cancers
Boris Brkljačić
; Department of Diagnostic and Interventional Radiology, Breast Unit, University Hospital Dubrava University of Zagreb School of Medicine, Zagreb, Croatia
Eugen Divjak
; Department of Diagnostic and Interventional Radiology, Breast Unit, University Hospital Dubrava University of Zagreb School of Medicine, Zagreb, Croatia
Čedna Tomasović-Lončarić
; Department of Pathology, University Hospital Dubrava,University of Zagreb School ofMedicine, Zagreb, Croatia
Vanja Tešić
; Department of Epidemiology Institute of Public Health “dr. Andrija Štampar,” Zagreb, Croatia
Gordana Ivanac
; Department of Diagnostic and Interventional Radiology, Breast Unit, University Hospital Dubrava University of Zagreb School of Medicine, Zagreb, Croatia
Sažetak
Aim To evaluate shear-wave elastographic (SWE) and related
gray-scale features of pure invasive lobular breast carcinoma
(ILC) and compare them with invasive ductal breast
cancers (IDC).
Methods Quantitative SWE features of mean (El-mean),
maximum (El-max), minimum (El-min) elasticity values of
the stiffest portion of the mass, and lesion-to-fat elasticity
ratio (E-ratio) were measured in 40 patients with pure ILC
and compared with 75 patients with IDC. Qualitative grayscale
features of lesion size, echogenicity, orientation, and
presence of distal shadowing were determined and compared
between the groups.
Results ILC were significantly larger than IDC (P = 0.008)
and exhibited significantly higher El-max (P = 0.015) and
higher El-mean (P = 0.008) than IDC. ILC were significantly
more often horizontally oriented, while IDC were significantly
more often vertically oriented (P < 0.001); ILC were
significantly more often hyperechoic than IDC (P < 0.001).
Differences in stiffness between ILC and IDC determined
by quantitative SWE parameters were present only in small
tumors (≤1.5 cm in size), ie, small ILC had significantly
higher El-max (P = 0.030), El-mean (P = 0.014), and El-min
(P = 0.045) than small IDC, while tumors larger than 1.5 cm
had almost equal stiffness, without significant differences
between the groups.
Conclusion Specific histopathologic features of ILC are
translated into their qualitative sonographic and quantitative
sonoelastographic appearance, with higher stiffness of
small ILC compared to small IDC. Gray-scale and sonoelastographic
features may help in diagnosing ILC.
Ključne riječi
Hrčak ID:
169152
URI
Datum izdavanja:
15.2.2016.
Posjeta: 1.219 *