Liječnički vjesnik, Vol. 135 No. 11-12, 2013.
Professional paper
CLINICAL GUIDELINES FOR DIAGNOSING, TREATMENT AND MONITORING PATIENTS WITH BLADDER CANCER – CROATIAN ONCOLOGY SOCIETY AND CROATIAN UROLOGY SOCIETY, CROATIAN MEDICAL ASSOCIATION
Marija Gamulin
Ira Pavlović Ružić
Mislav Grgić
Marijana Jazvić
Mladen Solarić
Dag Zahirović
Robert Zorica
Tomislav Omrčen
Marija Petković
Mate Matić
Željko Fučkar
Boris Ružić
Josip Pasini
Marijan Šitum
Gordana Đorđević
Damir Miletić
Tade Tadić
Željko Kaštelan
Davor Librenjak
Ivan Gilja
Katarina Vilović
Božo Krušlin
Hrvoje Kuveždić
Abstract
Urothelial cancer is the most common bladder cancer. Hematuria is the most common presenting symptom in patients with bladder cancer. The most common diagnostics of bladder cancer is performed by transurethral resection of bladder after which pathohistological diagnosis is set. It is necessary to determine whether the cancer penetrated in muscle layer (muscle-invasive cancer) or not (muscle-noninvasive cancer). Decision on therapeutic modality depends on the clinical stage of disease and on prognostic and risk factors. For muscle non-invasive bladder cancer transurethral resection is preferred with or without intravesical instillation of Bacillus Calmette-Guérin (BCG). For invasive cancer the method of choice is radical cystectomy. Radiotherapy is used in radical and palliative purposes. Metastatic disease is most frequently treated by chemotherapy metotrexate/vinblastine/doxorubicine/cisplatin (MVAC) or gemcitabine/cisplatin (GC). The purpose of this article is to present clinical recommendations to set standards of procedures and criteria in diagnostics, treatment and follow up of patients with bladder cancer in the Republic of Croatia.
Keywords
Urinary bladder neoplasms – diagnosis, pathology, therapy; Practice guidelines as topic; Croatia
Hrčak ID:
172511
URI
Publication date:
30.12.2013.
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