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Ecdysteroids. Selective Protections and Synthesis of Potential Tools for Biochemical Studies

Denis Guedin-Vuong ; Centre de Neurochimie CNRS, Universite Louis Pasteur, 5 rue Blaise Pascal, 67084,Strasbourg, France
Yoichi Nakatani ; Centre de Neurochimie CNRS, Universite Louis Pasteur, 5 rue Blaise Pascal, 67084,Strasbourg, France
Guy Ourisson ; Centre de Neurochimie CNRS, Universite Louis Pasteur, 5 rue Blaise Pascal, 67084,Strasbourg, France

Sažetak

B-Ecdysone and cyasterone bave been transformed into the ecdysterone analogue 4, wbich carries a [3-(p-hydroxyphenyl).-propoxylj- group at the end of the side chain. This derivative should be useful for various biochemical investigations (I-labelling, affinity chromatography), since it exhibits a marked ecdysterone-like activity in two independent biological tests. The synthetic scheme makes use of highly selective protections of the hydroxyl groups of phytoecdysteroids.

Ključne riječi

Hrčak ID:

178044

URI

https://hrcak.srce.hr/178044

Datum izdavanja:

6.3.1986.

Posjeta: 820 *