Other

https://doi.org/10.20471/acc.2016.55.04.21

A rare case of infectious multifocal serpiginoid choroiditis

Miloš Mitrašević ; Department of Hospital Healthcare, Faculty of Medical Sciences, Kragujevac, Serbia
Svetlana Jovanović ; Clinical Department of Ophthalmology, Faculty of Medical Sciences, Kragujevac, Serbia
Filip Radotić ; Faculty of Medical Sciences, Kragujevac, Serbia
Snežana Pešić ; Faculty of Medical Sciences, Kragujevac, Serbia
Zorica Jovanović ; Department of Pathophysiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia

Abstract

Multifocal serpiginoid choroiditis is an infectious variety of serpiginous choroiditis. The disease is characterized by infectious etiology and overlapping clinical features in an intermediary form of acute posterior multifocal placoid pigment epitheliopathy and serpiginous choroiditis. In a 33-year-old patient, bilateral multiple placoid partially confluent chorioretinal lesions were diagnosed after a febrile flu-like episode. On the right eye, there was a progressive decrease in visual acuity. Later, the lesions had a prolonged progressive devastating clinical course and widespread distribution of placoid lesions, and took the form of serpiginoid choroiditis. We conducted extensive laboratory
work-up and ancillary investigation for granulomatous diseases such as tuberculosis and sarcoidosis, and the results were not consistent with these entities. Systemic medical work-up revealed a history of
exposure to the human immunodeficiency virus, herpes simplex virus 1, varicella zoster virus and cytomegalovirus. The titer of Mycoplasma pneumoniae IgM antibodies was positive. After serological analysis positive for Mycoplasma pneumoniae, systemic antibiotic therapy and anti-inflammatory doses of corticosteroids were administered. Improvement of visual acuity after the introduction of causal antibiotic therapy in combination with anti-inflammatory therapy confirmed our suspicion that Mycoplasma pneumoniae was the etiologic cause of multifocal serpiginoid choroiditis.

Keywords

Acute posterior multifocal placoid pigment epitheliopathy; Serpiginoid choroiditis; Serpiginous choroiditis; Mycoplasma pneumoniae

Hrčak ID:

178135

URI

https://hrcak.srce.hr/178135

Publication date:

15.12.2016.

Article data in other languages: croatian

Visits: 1.805 *