Skoči na glavni sadržaj

Arhiv za higijenu rada i toksikologiju, Vol. 15 No. 3, 1964.

Izvorni znanstveni članak

Protective effects of some cholinolytics in armine poisoning

B. Bošković ; Farmakološki institut Medicinskog fakulteta, Sarajevo
D. Potkonjak ; Farmakološki institut Medicinskog fakulteta, Sarajevo
P. Stern ; Farmakološki institut Medicinskog fakulteta, Sarajevo

Puni tekst: bosanski pdf 7.272 Kb

str. 263-268

preuzimanja: 400

citiraj

Sažetak

Nine cholinolytics and one choline aoetylase inhiihitor (Morin) have been examined as potential protecting agents against armine poisoning. Only Hydroxyzine, Disipal and Ponalid were found to protect mice against one LD50 of armine. In combination with pyridine 2-aldoxime methchloride (PAM-2-Cl) the best effect was found with Aturban, which protected 50 per cent of mice against 4 mg/kg of armine (X LD50). The quaternary cholinolytics Antrenyl and atropine, combined with PAM-2-Cl, protected about 50 per cent of animals against 4 X LD50 of armine, similarly to a combination of central cholinolytics. Tropenzylium and Hydroxyzine. Other cholinolytics showed weaker protective properties.

Ključne riječi

Hrčak ID:

180443

URI

https://hrcak.srce.hr/180443

Datum izdavanja:

21.9.1964.

Podaci na drugim jezicima: bosanski

Posjeta: 1.278 *