Original scientific paper

https://doi.org/10.24099/vet.arhiv.160509

Acid-base balance during volatile and total intravenous anaesthesia in dogs

Hrvoje Capak ; Department of Radiology, Ultrasound Diagnostic and Physical Therapy, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Zrinka Filipović-Genter ; Veterinary practice “Pets2Vets”, Koprivnica, Croatia
Višnja Nesek-Adam ; Department of Anaesthesiology, Resuscitation and Intensive Care, Sveti Duh General Hospital, Zagreb, Croatia
Silvijo Vince ; Clinic of Obstetric and Reproduction, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Srećko Solina ; PhD student, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Damir Milas ; PhD student, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Darko Capak ; Clinic of Surgery, Orthopaedics and Ophthalmology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia

Abstract

The aim of this study was to compare the effects of two different anesthetic techniques on the acid base balance in bitches. Research was carried out on 20 bitches randomly divided into two groups. In group A general anaesthesia was induced by intravenous application of ketamine and diazepam, and maintained with an additional intravenous bolus of ketamine. In group B a combination of propofol and ketamine was used for induction of anaestesia. General anaesthesia was maintained with N2O and O2 in a range of 1:1 in combination with 2% isoflurane. Animals in both groups were kept on spontaneous ventilation. Arterial blood for blood gas analysis was taken at two time points (3 and 45 min. after induction of anaesthesia, respectively). Group A had a significantly (P<0.05) higher pH value than Group B at 45 min. The pCO2 was significantly (P<0.05) lower in group A than in group B at 3 and 45 min, respectively. There was also a significant difference in values of pO2 between the groups at 3 and 45 min. The pO2 was lower in group A than in group B. Group B had a significantly (P<0.05) higher HCO3- value than Group A at 45 min. Volatile anaesthesia minimally disturbs acid-base balance, and oxygen access capability is better.

Keywords

acid-base balance; inhalation anaesthesia; total intravenous anaesthesia; dogs

Hrčak ID:

180784

URI

https://hrcak.srce.hr/180784

Publication date:

3.5.2017.

Article data in other languages: croatian

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