Izvorni znanstveni članak
Clotting changes induced by metal ions in vitro
I. Šimonović
; Department of Medicine, Medical Faculty, University of Zagreb
Krista Kostial
; Institute for Medical Research (incorporating the Institute' of Industrial Hygiene), Zagreb
Anica Maršić
; Institute for Medical Research (incorporating the Institute' of Industrial Hygiene), Zagreb
Sažetak
Addition of UO2++, Sr++ and Pb++ to plasma in concentrations from 12,5-62,5 µg/ml does not influence the prothrombin activity. Mercury ions cause a prolongation of the plasma prothrombin time resulting in a reduction of the prothrombin index values to about 55%. This effect of mercury depends on the concentration of mercury ions and the exposure time. The highest reduction in prothrombin index values was observed at concentrations from 25,0-37,5 µg/ml after 3 hours of exposure. At higher or lower concentrations the effect was less pronounced.
Ključne riječi
Hrčak ID:
183009
URI
Datum izdavanja:
14.9.1959.
Posjeta: 780 *