Pregledni rad
MANAGEMENT OF CARDIOVASCULAR RISK FACTORS IN RHEUMATOID ARTHRITIS
MARIJA GLASNOVIĆ
; Sveučilište J. J. Strossmayera u Osijeku, Medicinski fakultet, Osijek, Klinički bolnički centar Osijek, Klinika za unutarnje bolesti, Osijek, Hrvatska
ALEKSANDAR VČEV
; Sveučilište J. J. Strossmayera u Osijeku, Medicinski fakultet, Osijek, Klinički bolnički centar Osijek, Klinika za unutarnje bolesti, Osijek, Hrvatska
ELIZABETA HORVATIĆ
; Opća bolnica Dr. Tomislav Bardek, Odjel za patologiju i citologiju, Koprivnica, Hrvatska
ŽELJKA KOLAK
; Opća županijska bolnica Vinkovci, Vinkovci, Hrvatska
VALENTINA MATIJEVIĆ
; Klinički bolnički centar Sestre milosrdnice, Klinika za reumatologiju, fizikalnu medicinu i rehabilitaciju, Zagreb, Hrvatska
DOMINIK GJONI
; Sveučilište J. J. Strossmayera u Osijeku, Medicinski fakultet, Osijek, Hrvatska
STEFAN GJONI
; Sveučilište J. J. Strossmayera u Osijeku, Medicinski fakultet, Osijek, Hrvatska
FABIAN GJONI
; Sveučilište J. J. Strossmayera u Osijeku, Medicinski fakultet, Osijek, Hrvatska
Sažetak
Patients with infl ammatory rheumatic diseases, particularly rheumatoid arthritis (RA), have a signifi cantly increased risk of cardiovascular (CV) disease compared to the general population. This particularly refers to the increased risk of myocardial infarction and ischemic heart disease. CV events and mortality rate in RA are by 40%-50% higher as compared with general population and the risk of ischemic heart disease is slightly higher than that of stroke. The risk increase in RA is initiated by a complex interaction between traditional and non-traditional factors of CV risk, where infl ammation, through direct or indirect harmful effects on vascular system, plays an important role. The infl ammation in RA is crucial for the development of CV risk and is an independent risk factor for the increased incidence of CV diseases. Patients having stronger disease activity in RA have an increased risk of developing heart failure. Doctors of medicine should be aware of the high CV risk and provide good control and treatment of CV diseases in RA patients.
Ključne riječi
rheumatoid arthritis; cardiovascular risks; inflammation
Hrčak ID:
218947
URI
Datum izdavanja:
4.4.2019.
Posjeta: 2.881 *