Original scientific paper
https://doi.org/10.20471/acc.2019.58.s2.02
Prostate-Specific Antigen (PSA) Values in Patients with Low- and High-Risk Prostatic Adenocarcinoma
Silvija Mašić
; Ljudevit Jurak Department of Pathology and Cytology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Ivan Pezelj
orcid.org/0000-0001-7083-7672
; Department of Urology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Božo Krušlin
orcid.org/0000-0002-0480-1687
; Ljudevit Jurak Department of Pathology and Cytology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; Department of Pathology, School of Medicine, University of Zagreb, Zagreb, Croatia
Abstract
Prostatic adenocarcinoma (PC) comprises around 19% of malignancies in Croatian male population. On the basis of PSA value, Gleason score, grading group and clinical stage, PC can be classified into low- and high-risk groups which is significant for different therapeutic regimens and prognostic outcomes. In this retrospective study, we analyzed the difference in preoperative PSA value in a group of 272 patients who underwent radical prostatectomy and were diagnosed with PC adenocarcinoma in our institution in a period from January 1st, 2018 untill December 31st, 2018. Subsequently, they were divided into low- and high-risk prostatic adenocarcinoma groups. Our results demonstrated positive correlation in preoperative PSA values between the groups and therefore support the use of PSA as one of the parameters in defining low- and high-risk prostatic adenocarcinoma categories.
Keywords
Prostatic Adenocarcinoma; PSA; Gleason Grade; Low-risk; High-risk
Hrčak ID:
233411
URI
Publication date:
1.11.2019.
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