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Acta clinica Croatica, Vol. 58. No. 4., 2019.

Original scientific paper

https://doi.org/10.20471/acc.2019.58.04.04

The Role of Cigarette Smoking and Alcohol Consumption in Pulmonary Tuberculosis Development and Recurrence

Marina Lampalo orcid id orcid.org/0000-0001-9264-6922 ; Jordanovac University Department for Lung Diseases, Zagreb University Hospital Centre, Zagreb, Croatia
Irena Jukić ; Croatian Institute of Transfusion Medicine, Zagreb, Croatia; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Jasna Bingulac-Popović ; Department of Molecular Diagnosis, Croatian Institute of Transfusion Medicine, Zagreb, Croatia
Hana Safić Stanić ; Croatian Institute of Transfusion Medicine, Zagreb, Croatia; School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Blaženka Barišić ; Jordanovac University Department for Lung Diseases, Zagreb University Hospital Centre, Zagreb, Croatia
Sanja Popović-Grle ; Jordanovac University Department for Lung Diseases, Zagreb University Hospital Centre, Zagreb, Croatia

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Abstract

During a two-year period (2001-2003), 464 patients were treated for tuberculosis at Jordanovac Department for Lung Diseases in Croatia. Besides pulmonary tuberculosis in 97.7% of patients, patients were also treated for tuberculous pleurisy (0.9%), tuberculous laryngitis (0.6%), tuberculous meningitis (0.2%), tuberculous pericarditis (0.2%) and urogenital tuberculosis (0.4%). Out of the total number of patients, 57.3% declared themselves to be active smokers (men were predominant and made up to 80.8%) and 20.9% to be active alcohol consumers. Both risk factors, i.e. smoking and alcohol consumption, were present in 15.1% of all patients. The most common comorbidities were diabetes mellitus (30.4%), cardiac diseases (11.2%) and chronic obstructive pulmonary disease (8.0%). Lung carcinoma was the most common malignant disease (n=51), with Mycobacterium tuberculosis
isolated in 33% of them. Seventy-two of 464 (15.5%) patients had recurrences of tuberculosis. Of these, 30.5% had one of the risk factors (20.8% were smokers and 9.7% consumed alcohol), while 32.5% of patients had both risk factors. In conclusion, cigarette smoking was proved to be the most significant risk factor for development of pulmonary tuberculosis and its recurrence.

Keywords

Tuberculosis; Cigarette smoking; Alcoholism; Mycobacterium tuberculosis; Croatia

Hrčak ID:

235082

URI

https://hrcak.srce.hr/235082

Publication date:

1.12.2019.

Article data in other languages: croatian

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