Medicina, Vol. 43. No. 4., 2007.
Ostalo
AGE INFLUENCE ON OVARY AND UTERUS DIMENSION, MORPHOLOGY AND VASCULARISATION
Ulla Marton
; Poliklinika Dr. Marton, Zagreb, Hrvatska
Sažetak
Three dimensional ultrasonographic measurements and
color and pulsed Doppler evaluation allow detailed
analysis of the ovarian volume, antral follicle number,
assessment of the ovarian stromal vascularity, as well as
evaluation of the endometrial receptivity in patients
undergoing IVF procedures. Results of our study indicate
that the best prognostic parameter in determination
of number of the oocytes in ovarian stimulation
protocols for IVF/ET treatment is number of antral follicles.
Other parameters such as flow index (FI) and
ovarian volume assessed by 3D ultrasound are less sensitive.
Significant decrease of the ovarian volume, number
of antral follicles and flow index was noticed with ageing
of the patients. These parameters had shown the
opposite trend regarding the fertilization rates in medically
assisted reproductive procedures. Patients with
small ovarian volume, few antral follicles and poor intraovarian vascularity may benefit from higher dose of
gonadotropins and different stimulation protocol.
Although the total number of follicles, ovarian volume,
and mean ovarian stromal vascularity decrease with age,
high pregnancy rates may be achieved even in older
patients in whom three dimensional variables are considered
normal. In addition to ovarian measurements,
endometrial volume measurements and assessment of
endometrial perfusion by 3 D power Doppler histogram
on the day of embryo transfer could be used for determination
of uterine receptivity in deciding how many
embryos or blastocysts will be transferred or cryopreserved.
Therefore, ovarian and endometrial measurements
by tree dimensional ultrasound may become
simple additional tests which could predict response to
stimulating drugs, degree of endometrial receptivity and
outcome of assisted reproductive techniques.
Ključne riječi
uterus; ultrasonography; assisted reproduction
Hrčak ID:
23478
URI
Datum izdavanja:
20.12.2007.
Posjeta: 5.916 *