Medicina, Vol. 57 No. 2, 2021.
Stručni rad
https://doi.org/10.21860/medflum2021_371667
Analysis of the potentially unnecessary medications in hospice care using OncPal guidelines for deprescription
Marin Golčić
orcid.org/0000-0002-3388-4813
; Klinka za radioterapiju i onkologiju, KBC Rijeka, Rijeka, Hrvatska
Renata Dobrila-Dintinjana
; Klinka za radioterapiju i onkologiju, KBC Rijeka, Rijeka, Hrvatska
Goran Golčić
; Klinka za radioterapiju i onkologiju, KBC Rijeka, Rijeka, Hrvatska
Lidija Gović-Golčić
; Ordinacija opće medicine, Rijeka, Hrvatska
Vera Vlahović-Palčevski
; Odjel za kliničku farmakologiju, KBC Rijeka, Rijeka, Hrvatska; Sveučilište u Rijeci, Medicinski fakultet, Zavod za farmakologiju, Rijeka, Hrvatska
Sažetak
Abstract. Aim: Deprescription is defined as stopping, limiting the dose, or replacing the medications in patients with a progressive and incurable disease in order to achieve the highest possible quality of life. Palliative care patients use a variety of medications during their last days, which can increase the number of side-effects or reduce the effectiveness of the drugs. The goal of this article is to analyze potentially unnecessary drugs in hospice care using the OncPal guidelines for deprescription. Patients and methods: We retrospectively analyzed the use of potentially unnecessary mediations on 790 palliative care cancer patients treated in the „hospice Marija K. Kozulić“ in Rijeka, from 2013 to 2017, using the OncPal guidelines for deprescription. Results: On average, patients used 6 different medications a day. When focusing on 7 medication groups from 6 potentially unnecessary medication classes from OncPal guidelines, we found that the most commonly used medications were gastroprotectives, which were used in 61.9% patients, and potentially unnecessary in 30.6%. Antihypertensives were used by 39.6% of patients, and in 30.6% potentially unnecessary, along with 7.2% patients who used vitamins and minerals, or 6.3% who used statins. No patients used bisphosphonates. Anticoagulant drugs were used in 4.4% of patients and hypoglicemic drugs in 12.8%. Conclusion: Over two-thirds of patients treated in hospice care have at least 1 potentially unnecessary medication. Hence, it is crucial to develop the idea of deprescription and encourage the development and use of guidelines such as OncPal, in order to rationalize the pharmacotherapy in palliative care patients and achieve maximum quality of life.
Ključne riječi
deprescription; hospice care; palliative care; guidelines
Hrčak ID:
255669
URI
Datum izdavanja:
1.6.2021.
Posjeta: 2.159 *