Izlaganje sa skupa
INTENSITY OF SYMPTOMS FROM ALCOHOL WITHDRAWAL IN ALCOHOL-DEPENDENT PATIENTS: COMPARISON BETWEEN SMOKERS AND NON-SMOKERS
Denis Jacques
; Mont-Godinne University Clinics, Psychosomatic Unit, 5530 Yvoir, Belgium
Nicolas Zdanowicz
; Mont-Godinne University Clinics, Psychosomatic Unit, 5530 Yvoir, Belgium
Christine Reynaert
; Mont-Godinne University Clinics, Psychosomatic Unit, 5530 Yvoir, Belgium
Pascal Janne
; Mont-Godinne University Clinics, Psychosomatic Unit, 5530 Yvoir, Belgium
Philippe Timary
; Saint-Luc University Clinics, Psychopathology, 1200 Brussels, Belgium
Sažetak
Background: in patients with a dual dependence on alcohol and tobacco, the spontaneous discourse among doctors is not to
encourage them to consider preparing to give up both substances. The argument put forward is that withdrawal would be more
difficult. We wanted to compare the intensity of withdrawal symptoms in patients hospitalised for alcohol detoxification between
smokers and non-smokers.
Subject and methods: We compared patients hospitalised for alcohol detoxification who smoke versus non-smokers who received
replacement therapy through benzodiazepines and not nicotine replacement. The blood pressure and the cardiac frequency measure
on the first day of hospitalisation, the doses of Diazepam dispensed on the first day, and the Clinical Institute Withdrawal Assessment
of Alcohol Scale Revised (CIWA-Ar) score on the second day were compared.
Results: a trend emerged whereby smoking patients undergoing alcohol detoxification showed higher blood pressure, higher
cardiac frequency and required higher doses of benzodiazepines on the first day of hospitalisation. Patients who smoke also had
higher CIWA-Ar scores on the second day of hospitalisation.
Discussion: from a physiological point of view, the intensity of the symptoms of alcoholic withdrawal seems to be greater in
hospitalised patients who smoke vs. non-smokers in the first two days. Does giving up both substances at the same time result in
fewer withdrawal symptoms? And in this case, should a double replacement be recommended: benzodiazepines and nicotine
replacement therapy?
Conclusion: to be able to refine the recommendations on alcohol-tobacco dual withdrawal programmes, other studies are
needed to compare giving up both substances with or without nicotine replacement.
Ključne riječi
alcohol; tobacco; withdrawal; blood pressure; cardiac frequency; CIWA
Hrčak ID:
264696
URI
Datum izdavanja:
1.9.2011.
Posjeta: 181 *