Izlaganje sa skupa
CO-MORBIDITY PART 2 - NEUROBIOLOGY AND SUICIDE RISK; MODELLING THE CONSEQUENCES OF BIPOLAR AND ANXIETY CO-MORBIDITY
Mark Agius
; Department of Psychiatry University of Cambridge, Cambridge, UK ; Clare College Cambridge, Cambridge, UK ; South Essex Partnership University Foundation Trust, UK
Norma Verdolini
; School of Specialisation in Psychiatry University of Perugia, Perugia, Italy
Francesca Falzon Aquilina
; Mater Dei Hospital, Malta
Sophie Butler
; South London and Maudsley NHS Foundation Trust, UK
Sažetak
We review the evidence that Bipolar Disorder with Comorbid Anxiety, Rapid Cycling Bipolar Disorder, Mixed Affective states,
are all related to each other and to Dopamine Transmission in Bipolar Disorder. All these states are related to the presence of
particular polymorphisms of the genes of the D2 andD3 receptors. All these states increase the risk of suicidality. Substance and
alcohol abuse comorbid with bipolar disorder increases the risk of both Rapid Cycling and Suicidality.We present a model which
demonstrates these relationships.
Ključne riječi
Bipolar Disorder with Comorbid Anxiety; Rapid Cycling Bipolar Disorder; Mixed Affective states; Dopamine Transmission; D2 receptor; D3 receptor; suicidality
Hrčak ID:
265739
URI
Datum izdavanja:
5.11.2014.
Posjeta: 166 *