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PREVALENCE OF GESTATIONAL DIABETES MELLITUS AND PERINATAL OUTCOMES ACCORDING TO THE OLD WHO CRITERIA AND IADPSG CRITERIA
Mato Pavic
; Clinic for Women's Diseases and Obstetrics, University Hospital Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Vedran Premuzic
; School of Medicine, University of Zagreb, Zagreb, Croatia ; Department of Nephrology, Hypertension, Dialysis and Transplantation, University Hospital Zagreb, Zagreb, Croatia
Ana Zovak Pavic
; Community Health Center Zagreb East, Outpatient Clinic for Gynecology, Zagreb, Croatia
Milenko Bevanda
; School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina
Slobodan Mihaljevic
; School of Medicine, University of Zagreb, Zagreb, Croatia; Department of Anesthesiology, Reanimatology and Intensive Care Medicine, University Hospital Zagreb, Zagreb, Croatia received:
Slavko Oreskovic
; Clinic for Women's Diseases and Obstetrics, University Hospital Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Sažetak
Background: Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnancy. Pregnancies with
GDM have worse outcomes compared to pregnancies with normal glucose tolerance. The objectives of the study were to determine
the prevalence of GDM and perinatal outcomes according to the old WHO criteria and IADPSG criteria.
Subjects and methods: A retrospective study included 2,405 pregnant women who delivered between January 2009 and
December 2010. According to the OGTT results, pregnant women were divided into 4 groups. We analyzed the prevalence of GDM,
characteristics of pregnant women and their newborns and perinatal outcomes.
Results: We found significantly higher prevalence of GDM according to the IADPSG criteria compared to the WHO criteria.
Pregnant women with GDM were significantly older, had higher pre-pregnancy BMI, fasting and 2-h plasma glucose. Pregnant
women with GDM had worse pregnancy outcomes compared to control group. The overall proportion of overweight and obese
pregnant women was the highest in the group of untreated pregnant women with GDM according to the IADPSG criteria. In this
group we found significantly higher rate of fetal macrosomia and LGA. The rate of caesarean section was significantly higher in
comparison to control group. Pre-eclampsia was significantly more common in groups of pregnant women with GDM compared to
control group.
Conclusion: IADPSG diagnostic criteria reveals more women with hyperglycemic disorders in pregnancy. A group of
pregnant women who were normoglycemic according to the WHO criteria, but according to the IADPSG were diagnosed GDM,
had adverse pregnancy outcomes. Lower values of glycemia, than those defined for diabetes in pregnancy, are associated with
adverse pregnancy outcomes.
Ključne riječi
GDM; WHO; IADPSG; pregnancy outcome
Hrčak ID:
266970
URI
Datum izdavanja:
4.10.2021.
Posjeta: 327 *