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IMPACT OF INVASIVE EEG MONITORING AND RESECTIVE NEUROSURGICAL TREATMENT ON THE QUALITY OF LIFE IN PATIENTS WITH DRUG RESISTANT EPILEPSY - PRELIMINARY RESULTS
Dragana Mijatović
; Istrian Health Center, Umag Section, Umag, Croatia
Željka Petelin Gadže
; Department of Neurology, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy, Zagreb, Croatia
Filip Đerke
; Health Centre Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia
Goran Mrak
; Department of Neurosurgery, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia
Ratimir Petrović
; 6Department of Nuclear Medicine and Radiation Protection, University Hospital Zagreb, Zagreb, Croatia
Andrica Lekić
; Department of Basic Medical Sciences, Faculty of Health Studies, University of Rijeka, Rijeka, Croatia
Sažetak
Background: Neurosurgical treatment is one of important way to cure drug resistant epilepsy. After invasive EEG monitoring
and the invasive neurosurgical treatment (resective surgery) there are possible complications (intracranial haemorrhage, cortic al
lesions and infections), however there are possible neuropsyhologic outcomes such as memory outcomes, language outcomes and
psychiatric outcomes. The quality of life in epilepsy (QOLIE-31) scale is a self-completed questionnaire which contains seven
subscales which address the following aspects: emotional well-being, social functioning, energy/fatigue, cognitive functioning,
seizure worry, medication effects and overall quality of life. Our study aimed to examine the quality of life in patients with drug
resistant epilepsy who had undergone invasive EEG monitoring and resective neurosurgical treatment through the application of t he
QOLIE-31 scale.
Subjects and methods: The study included 9 patients with drug resistant epilepsy who had undergone invasive EEG monitoring
followed by resective neurosurgical treatment in the period from 2010 to 2016, and the control group of 15 patients with drug
resistant epilepsy who had not undergone neurosurgical procedures. Clinical variables of interest for this study were obtained
through phone contact, and the QOLIE-31 scale was applied.
Results: In the domaine of seizure worry, patients in the examined group were more concerned about the seizures (54.7)
compared to the examined group (80), as well as in the overal quality of life (examined group 57.5; control group 77.5). Patien ts in
the control group complained more in the domain of antiepileptic therapy (score 70.7) than patients in the examined group (scor e
100). In the other domains: emotional well-being, energy/fatigue, cognitive functioning, and social functioning there were mino r
deviations between the examined and control groups.
Conclusion: There was no statistically significant difference between individual QOLIE-31 questionnaires, as well as between
the two groups of respondents.
Ključne riječi
drug resistant epilepsy; invasive EEG monitoring; epilepsy surgery; QOLIE-31
Hrčak ID:
269453
URI
Datum izdavanja:
21.12.2019.
Posjeta: 464 *