Acta clinica Croatica, Vol. 60. No. 3., 2021.
Original scientific paper
https://doi.org/10.20471/acc.2021.60.03.01
Difference in Predictors of Anastomotic Leakage Depending on the Level of Anastomosis after Colorectal Cancer Surgery
Damir Jašarović
; Department of General Surgery, Zemun University Hospital, Belgrade, Serbia
Dragoš Stojanović
; Department of General Surgery, Zemun University Hospital, Belgrade, Serbia
Nebojša Mitrović
; Department of General Surgery, Zemun University Hospital, Belgrade, Serbia
Dejan Stevanović
; Department of General Surgery, Zemun University Hospital, Belgrade, Serbia
Aleksandar Lazić
; Department of General Surgery, Zemun University Hospital, Belgrade, Serbia
Abstract
Anastomotic leak (AL) after colorectal cancer surgery is one of the most serious
postoperative complications which has major impact on outcomes. The aim of this study was to investigate
preoperative and intraoperative risk factors for AL, as well as to examine whether there are
differences in risk factors for AL depending on the primary tumor location. We retrospectively reviewed
records of patients having undergone colorectal surgical procedures for malignancies between
January 2013 and December 2017 in a single institution. Only procedures with primary anastomosis
were included. Of the 153 patients, AL occurred in 10.6% of patients with primary tumor in the sigmoid
colon and rectum, and in 8.2% of patients with primary tumor in the proximal sections of the
colon. On univariate analysis, delayed oral intake and more advanced histologic stages of the tumor
were significantly correlated with AL in patients with tumors in the sigmoid colon and rectum, and
multiorgan resection and distant metastases in patients with tumors in the proximal sections of the
colon. In conclusion, risk factors for the occurrence of AL vary depending on the primary tumor location
and further investigation is needed to provide better insight into these differences.
Keywords
Colorectal cancer; Anastomotic leak; Risk factors; Rectal cancer; Colon cancer
Hrčak ID:
271320
URI
Publication date:
1.9.2021.
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