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https://doi.org/10.24141/1/8/1/4
Serum Concentration of Vitamin D in Patients with Vulgar Psoriasis
Marina Vekić Mužević
; KBC Osijek, Zavod za dermatologiju i venerologiju, Osijek, Hrvatska ; Katedra za infektologiju i dermatovenerologiju, Medicinski fakultet, Sveučilište Josipa Jurja Strossmayera u Osijeku, Osijek, Hrvatska
Tatjana Matijević
; KBC Osijek, Zavod za dermatologiju i venerologiju, Osijek, Hrvatska
Irina Bagić
; KBC Osijek, Klinika za neurokirurgiju, Osijek, Hrvatska ; Medicinski fakultet, Sveučilište Josipa Jurja Strossmayera u Osijeku, Osijek, Hrvatska
Vjenceslav Vrtarić
; KBC Osijek, Klinika za neurokirurgiju, Osijek, Hrvatska ; Medicinski fakultet, Sveučilište Josipa Jurja Strossmayera u Osijeku, Osijek, Hrvatska
Elvira Lazić Mosler
; Odjel za dermatologiju i venerologiju, Opća bolnica „dr. Ivo Pedišić“, Sisak, Hrvatska ; Medicinski fakultet, Hrvatsko katoličko sveučilište, Zagreb, Hrvatska
Sažetak
Introduction: Psoriasis is a chronic, inflammatory systematic disease that primarily affects the skin. Various factors influence the disease outcome and severity, among which the influence of vitamin D serum levels could potentially be important for disease pathogenesis and therapeutic strategies.
Aim: To analyze vitamin D serum levels in patients with psoriasis in comparison to healthy individuals, together with markers of inflammation and disease severity.
Methods: The study included patients with psoriasis that formed the case group, while the control group consisted of healthy individuals. The investigated features were demographical data, body mass index (BMI), disease severity, vitamin D serum levels, inflammatory markers, and parathyroid hormone (PTH) levels.
Results: The study included 112 participants, 60 in the case group and 52 in the control group with the median age of 49 years. Physical activity was higher in the control group, while the body mass and the BMI were higher in the case group. Participants’ BMI negatively correlated to vitamin D serum levels, as well as C-reactive protein values in the control group and PTH in the case group. There was no significant difference in nicotine and alcohol consumption, sun exposure or vitamin D levels between the two groups.
Conclusion: Both groups presented with vitamin D serum levels in the deficiency range. The seasons of the year and the participants’ BMI affected vitamin D status. Vitamin D levels were equally distributed between the groups without influence on disease severity.
Ključne riječi
psoriasis; vitamin D; body mass index; parathyroid hormone; C-reactive protein
Hrčak ID:
271947
URI
Datum izdavanja:
3.2.2022.
Posjeta: 1.115 *