Izvorni znanstveni članak

Sensitive determination of uric acid at layered zinc hydroxide-sodium dodecyl sulphate-propoxur nanocomposite

Mohamad Hafiz Ahmad Tajudin ; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
Mohamad Syahrizal Ahmad orcid.org/0000-0002-9278-6332 ; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
Illyas Md Isa ; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
Norhayati Hashim ; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
Anwar Ul-Hamid ; Center for Engineering Research, Research Institute, King Fahd University of Petroleum & Minerals, Dhahran 31261, Saudi Arabia
Mohamad Idris Saidin ; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
Rahadian Zainul ; Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang, West Sumatera 25171, Indonesia
Suyanta M. Si ; Department of Chemistry Education, Faculty of Mathematics and Natural Science, Yogyakarta State University, Indonesia

Sažetak

An electrochemical chemical sensor for the determination of uric acid (UA) with high sen­si­ti­vity and a wide working range was fabricated using the layered zinc hydroxide-sodium dode­cyl sulphate-propoxur (LZH-SDS-PRO) nanocomposite, modified with multi­wall carbon nano­tu­bes (MWCNT). The introduction of LZH-SDS-PRO as a conducting matrix has en­hanced the con­ductivity of MWCNT. The morphology of LZH-SDS-PRO/MWCNT was cha­rac­terized by trans­mission electron microscopy (TEM) and scanning electron micro­scopy (SEM), while electro­chemical behavior of UA and K3[Fe(CN)6] at LZH-SDS-PRO/MWCNT paste electrode was studied by square wave and cyclic voltammetry, respect­tively. Under the opti­mized ex­peri­mental conditions, the electrode established linear plot for UA con­centrations 7.0 mol L-1 to 0.7 mmol L-1 (R2 = 0.9920) and LOD was calculated to be 4.28 µmol L-1 (S/N = 3). The fabri­ca­ted LZH-SDS-PRO/MWCNT electrode was success­sfully applied to urine samples, exhi­bi­t­ing excellent stability and reproducibility, which made it worthwhile for analytical applica­tions.

Ključne riječi

electrochemical sensor, pharmaceutical sensor, modified MWCNT, layered metal hydroxide, functional nanocomposite, square wave voltammetry

Hrčak ID:

273960

URI

https://hrcak.srce.hr/273960

Datum izdavanja:

7.3.2022.

Posjeta: 880 *