Recenzija, Prikaz slučaja
Vitiligo-like Depigmentation in a Patient Undergoing Treatment with Nivolumab for Advanced Renal-cell Carcinoma
Inigo Navarro-Fernandez
; Department of Dermatology, University Hospital Marqués de Valdecilla, Santander, Spain
Carmen Gonzalez- Vela
; Department of Pathology, University Hospital Marqués de Valdecilla, Santander, Spain
Cristina Gomez-Fernandez
; Department of Dermatology, University Hospital Marqués de Valdecilla, Santander, Spain
Carlos Duran- Vian
; Department of Dermatology, University Hospital Marqués de Valdecilla, Santander, Spain
Leandra Reguero
; Department of Dermatology, University Hospital Marqués de Valdecilla, Santander, Spain
Marcos Gonzalez- Lopez
; Department of Dermatology, University Hospital Marqués de Valdecilla, Santander, Spain
Sažetak
Nivolumab is a fully human monoclonal antibody
that targets the programmed cell death 1 (PD-1) immune
checkpoint. It has been approved for its use in
several types of advanced solid tumors, including melanoma,
lung cancer, and renal cell carcinoma (RCC).
The inhibition of PD-1 leads to an enhanced adaptive
immune response against tumor cells through the activation
of T-cells.
Ključne riječi
Hrčak ID:
274447
URI
Datum izdavanja:
17.3.2021.
Posjeta: 759 *