Pismo uredniku
Should Paraben Mix Be Removed from The European Baseline Series?
Inês Gonçalves Nunes
; Hospital and University Centre of Coimbra, Portugal Coimbra, Portugal
Maria Relvas
; Dermatology department. Hospital and University Centre of Coimbra, Coimbra, Portugal
Margarida Gonçalo
; Allergy and clinical immunology department. Hospital and University Centre of Coimbra, Coimbra, Portugal;
Sažetak
The European Baseline Series (EBS) of contact allergens
is used throughout Europe as a screening test
to diagnose contact allergy as a proxy for allergy contact
dermatitis and other hypersensitivity skin diseases
(1). Parabens are alkyl esters of p-hydroxybenzoic
acid with antimicrobial effects used as preservatives
in cosmetics, foods, and drugs that have been included
in the so called “baseline series” (2) for more than
40 years. Parabens, which are considered allergologically
safe biocides and are classified as safe by the US
Food and Drug Administration (FDA) and the Scientific
Committee on Consumer Safety (SCCS) in Europe
(2-4), are frequently present in cosmetics (5). Despite
extensive and progressively expanding use worldwide,
studies confirm that parabens are seldom responsible
for allergic contact dermatitis to cosmetics,
and the frequency of sensitivity to parabens has been
low and stable for many decades (2). The frequency
of positive reactions to paraben mix is less than 0.5%
in most clinical series, although it seems that when
it occurs it is often of high clinical relevance (6). Nevertheless,
several authors have stated that these patients
rarely or never have to avoid foods or cosmetics
that contain parabens to control their dermatitis (2).
Ključne riječi
Hrčak ID:
274607
URI
Datum izdavanja:
15.9.2021.
Posjeta: 448 *