Izvorni znanstveni članak

https://doi.org/10.20471/acc.2022.61.01.07

Impact of Chemotherapy-Induced Peripheral Neuropathy on the Quality of Life in Cancer Patients

Marica Novak orcid.org/0000-0003-0771-5028 ; Department of Oncology, Zagreb University Hospital Center, Zagreb, Croatia
Jasminka Miličević ; Department of Oncology, Zagreb University Hospital Center, Zagreb, Croatia
Vesna Bišof orcid.org/0000-0003-0771-5028 ; Department of Oncology, Zagreb University Hospital Center, Zagreb, Croatia; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia

Sažetak

The aim of the study was to investigate the correlation between chemotherapy-
induced peripheral neuropathy (CIPN) and quality of life, as well as to establish whether there
was a difference in peripheral neuropathy symptoms and their effect on the quality of life depending
on the type of agents applied. The study encompassed 156 patients treated at the Department of
Oncology from March to May 2017. Data were collected through self-reported questionnaires issued
by the European Organization for Research and Treatment of Cancer (EORTC QLQ-C30) and by
Chemotherapy-Induced Peripheral Neuropathy module (CIPN20). The results showed sensory and
motor neuropathy to be statistically significantly correlated with the general quality of life variables
of pain, tiredness, diarrhea, insomnia and breathing difficulty. Oxaliplatin had a significantly greater
effect on the onset of motor and sensory neuropathy than taxane and cisplatin/carboplatin. Nursing
interventions based on specific characteristics of certain chemotherapeutic agents should be developed
for CIPN alleviation.

Ključne riječi

Cancer; Oncology; Neuropathy; Oxaliplatin; Taxane; Cisplatin

Hrčak ID:

280117

URI

https://hrcak.srce.hr/280117

Datum izdavanja:

1.3.2022.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.845 *