Studija slučaja
Epidermolysis Bullosa Acquisita Mimicking Linear IgA Bullous Disease in a 5-year-old Child
Karen Manuelyan
orcid.org/0000-0003-1978-4696
; Department of Dermatology and Venereology, Medical Faculty, Trakia University, Stara Zagora, Bulgaria
Grisha Mateev
; Department of Dermatology and Venereology, Alexandrovska University Hospital, Medical University, Sofia, Bulgaria
Kossara Drenovska
; Department of Dermatology and Venereology, Alexandrovska University Hospital, Medical University, Sofia, Bulgaria
Martin Shahid
; Department of Dermatology and Venereology, Alexandrovska University Hospital, Medical University, Sofia, Bulgaria
Snejina Vassileva
; Department of Dermatology and Venereology, Alexandrovska University Hospital, Medical University, Sofia, Bulgaria
Sažetak
We present a case of a 5-year-old child with epidermolysis bullosa acquisita, clinically resembling linear IgA bullous disease.
The case demonstrates that autoimmune bullous dermatoses in childhood may show a clinical overlap, which makes the diagnosis based
on clinical features highly unreliable. Specific immunofluorescence and
immunoserological tests are crucial for precise diagnosis – in our case
circulating antibodies against collagen VII were detected using ELISA
and indirect immunofluorescence on transfected cells. The disease was
treated with systemic and topical steroids with excellent results.
Ključne riječi
epidermolysis bullosa acquisita, childhood, linear IgA dermatosis, immunofluorescence
Hrčak ID:
281279
URI
Datum izdavanja:
16.7.2020.
Posjeta: 791 *