Izvorni znanstveni članak

https://doi.org/10.24869/psyd.2022.752

EVALUATION OF NEUROPSYCHIATRIC COMPLICATIONS IN HOSPITALIZED COVID-19 PATIENTS

Aneta Bednarova ; 2nd Department of Psychiatry, Faculty of Medicine, Pavol Jozef Safarik University and University Hospital of L. Pasteur, Kosice, Slovakia
Jakub Sekula ; Department of Infectology and Travel Medicine, Pavol Jozef Safarik University and University Hospital of L. Pasteur, Kosice, Slovakia
Dorota Sopkova ; Department of Forensic Medicine, Faculty of Medicine, Pavol Jozef Safarik University, Kosice, Slovakia
Pavol Jarcuska ; Department of Infectology and Travel Medicine, Pavol Jozef Safarik University and University Hospital of L. Pasteur, Kosice, Slovakia

Sažetak

Background: Previous research has shown that COVID-19 patients are at risk of developing mental disorders. Limited number
of studies about psychiatric and neuropsychiatric presentations in hospitalized COVID-19 patients is currently available.
Subjects and methods: Subjects were 172 patients diagnosed with COVID-19 and requiring inpatient care, hospitalized at
reprofiled clinics of the university hospital. The study aimed to quantify psychiatric symptoms, and determine correlations with
agitation, BMI, mortality, and other variables (age, sex, oxygen therapy, intubation, etc.).
Results: Mental disorders due to known physiological conditions were of highest prevalence (n=105, 62.9%), followed by
anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders (n=34, 20.4%), and dementia (n=21,
12.6%) in COVID-19 patients. Depressive disorders (n=13, 7.9%), alcohol related disorders associated with withdrawal symptoms
(n=10, 6%), and schizophrenia, schizotypal, delusional, and other non-mood psychotic disorders (n=4, 2.4%) were less common.
Patients diagnosed with mental disorders due to known physiological conditions were significantly older compared to patients with
other diagnoses. The depression was observed more commonly in patients treated with high-flow nasal oxygen (HFNO), and patients
disconnected from invasive mechanical ventilation (IMV). Mixed anxiety-depressive symptoms were observed in 23.8% of the
patients (n=41), and they were more prevalent in younger patients compared to patients without anxiety-depressive symptoms.
Agitated patients were significantly older than non-agitated patients. No connection was observed between the occurrence of
agitation and treatment with HFNO, nor in case of patients disconnected from IMV; however, the relationship between agitation and
death proved to be statistically significant (OR = 5.9, 95% CI 2.33-15.29).
Conclusion: Analysis of psychiatric and neuropsychiatric presentations in COVID-19 patients and their correlation with
multiple variables provides a better understanding of the effect of infection on mental health, and brings forth a necessity of
transdisciplinary approach in handling COVID-19 patients.

Ključne riječi

COVID-19; anxiety; depression; coronavirus infection; sleep disorder; agitation

Hrčak ID:

291863

URI

https://hrcak.srce.hr/291863

Datum izdavanja:

22.12.2022.

Posjeta: 477 *