Review article

https://doi.org/10.21860/medflum2023_306342

CYFRA 21-1 Protein - a Potential Marker of Endometriosis

Alenka Višnić ; Klinički bolnički centar Rijeka, Klinika za ginekologiju i porodništvo, Zavod za humanu reprodukciju, Rijeka, Hrvatska
Gordana Čanadi Jurešić ; Sveučilište u Rijeci, Medicinski fakultet, Katedra za medicinsku kemiju, biokemiju i kliničku kemiju, Rijeka, Hrvatska
Dubravko Barišić ; Specijalna bolnica Radiochirurgia Zagreb, Zagreb, Hrvatska
Nataša Smajla ; Klinički bolnički centar Rijeka, Klinika za ginekologiju i porodništvo, Zavod za humanu reprodukciju, Rijeka, Hrvatska
Tina Sušanj Šepić ; Klinički bolnički centar Rijeka, Klinika za ginekologiju i porodništvo, Zavod za humanu reprodukciju, Rijeka, Hrvatska
Neda Smiljan Severinski ; Klinički bolnički centar Rijeka, Klinika za ginekologiju i porodništvo, Zavod za humanu reprodukciju, Rijeka, Hrvatska

Abstract

Endometriosis is a chronic gynaecological inflammatory disease characterized by the appearance and flourishing of endometrium outside the uterine cavity. The etiopathogenesis is not yet clearly understood. The ongoing pathologic processes are invasion, adhesion, proliferation, angiogenesis, and immune dysfunction. There is a possibility of increased production of proteins caused by proliferation and invasion, that are excreted in the urine. The protein CYFRA 21-1 shows increased production in endometriosis and is a potential marker in the early stages of this disease when it is not possible to suspect the disease or diagnose it with imaging techniques.

Keywords

Endometriosis; Proteins; Urine

Hrčak ID:

306342

URI

https://hrcak.srce.hr/306342

Publication date:

1.9.2023.

Article data in other languages: croatian

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