Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2022.63.33 5
Survival after hospital discharge in patients hospitalized for acute coronavirus disease 2019: data on 2586 patients from a tertiary center registry
Marko Lucijanić
; Hematology Department, Dubrava University Hospital, Zagreb, Croatia
Nevenka Piskač Živković
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Marko Zelenika
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Mislav Barišić-Jaman
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Ivana Jurin
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Ana Matijaca
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Nikola Zagorec
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Marko Lagančić
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Besa Osman
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Iva Bušić
; University of Zagreb, School of Medicine, Zagreb, Croatia
Sara Šakota
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Ivan Vukoja
; Gastroenterology and Nephrology Department, General County Hospital Požega, Požega, Croatia
Ivica Lukšić
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Bruno Baršić
; Primary Respiratory and Intensive Care Center, Dubrava University Hospital, Zagreb, Croatia
Sažetak
Aim To assess the long-term survival after hospital dis
-
charge of patients hospitalized due to coronavirus disease
2019 (COVID-19).
Methods We retrospectively reviewed data on post-dis
-
charge survival of 2586 COVID-19 patients hospitalized in
our tertiary hospital from March 2020 to March 2021.
Results Among 2586 patients, 1446 (55.9%) were men.
The median age was 70 years, interquartile range (IQR, 60-
80). The median Charlson comorbidity index was 4 points,
IQR (2-5). The median length of hospital stay was 10 days,
IQR (7-16). During a median follow-up of 4 months, 192
(7.4%) patients died. The median survival time after hos
-
pital discharge was not reached, and 3-month, 6-month,
and 12-month survival rates were 93%, 92%, and 91%, re
-
spectively. In a multivariate analysis, mutually independent
predictors of worse mortality after hospital discharge were
age >75 years, Eastern Cooperative Oncology Group status
4, white blood cell count >7 ×10
9
/L, red cell distribution
width >14%, urea on admission >10.5 mmol/L, mechani
-
cal ventilation during hospital stay, readmission after dis
-
charge, absence of obesity, presence of chronic obstructive
pulmonary disease, dementia, and metastatic malignancy (P<0.05 for all).
Conclusion Substantial risk of death persists after hospital
admission due to COVID-19. Factors related to an increased
risk are older age, higher functional impairment, need for
mechanical ventilation during hospital admission, param
-
eters indicating more pronounced inflammation, impaired
renal function, and particular comorbidities. Interventions
aimed at improving patients’ functional capacity may be
needed.
Ključne riječi
Hrčak ID:
306598
URI
Datum izdavanja:
25.8.2022.
Posjeta: 134 *