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Psychiatria Danubina, Vol. 35 No. 2, 2023.

Izvorni znanstveni članak

https://doi.org/10.24869/psyd.2023.199

THE RELATIONSHIP BETWEEN ATTACHMENT AND SERUM OXYTOCIN AND HEAT SHOCK PROTEIN-70 LEVELS IN ADOLESCENTS OF PARENTS WITH SCHIZOPHRENIA AND BIPOLAR DISORDER

Büşra Olcay Öz ; Department of Child and Adolescent Psychiatry, Düzce University Faculty of Medicine, Düzce, Turkey
Merve Alpay ; Department of Medical Biochemistry, Düzce University Faculty of Medicine, Düzce, Turkey
Şeyma Özge Kaban ; Department of Child and Adolescent Psychiatry, Düzce University Faculty of Medicine, Düzce, Turkey
Mehmet Ali Sungur ; Department of Biostatistics and Medical Informatics, Düzce University Faculty of Medicine, Düzce, Turkey
Ahmet Ataoğlu ; Department of Psychiatry, Düzce University Faculty of Medicine, Düzce, Turkey

Puni tekst: engleski pdf 526 Kb

str. 199-209

preuzimanja: 152

citiraj

Sažetak

Background: The aim of this study was to evaluate serum heat shock protein 70 (HSP70) and oxytocin levels, attachment and perceived social support levels in adolescents with parental bipolar disorder (BD) and Schizophrenia (SCZ).
Subjects and Methods: This study included 9 adolescents with SCZ parents, 30 adolescents with BD parents and 31 healthy adolescents. Brief Symptom Inventory (BSI), Relationship Scale Questionnaire-Adolescent Form (RSQ-A) and Multidimensional Scale of Perceived Social Support (MSPSS) were administered to all participants. In addition, serum HSP-70 and oxytocin levels were evaluated.
Results: There was no significant difference between the groups in terms of attachment style, psychiatric symptoms and perceived social support. Serum HSP-70 levels were found to be lower in adolescents whose parents had BD. Serum oxytocin levels of the SCZ group were significantly lower than those of the BD group.
Conclusions: HSP-70 level was found to be lower in adolescents with BD parents. Oxytocin level was found to be lower in adolescents with SCZ parents. These findings suggest that HSP-70 and oxytocin may be a marker of early life stress in adolescents with parental psychopathology. However, studies are needed to evaluate the relationship between attachment, oxytocin and HSP-70 in adolescents exposed to parental psychopathology in early life.

Ključne riječi

Attachment; adolescents; bipolar disorder; heat shock protein-70; oxytocin.

Hrčak ID:

306943

URI

https://hrcak.srce.hr/306943

Datum izdavanja:

17.7.2023.

Posjeta: 578 *