Review article
Subepidermal Basal Cell carcinoma Following Laser Treatment of Congenital Capillary Malformation: A Case Report
Krešimir Bulić
; University Hospital Centre Zagreb, Zagreb, Croatia
Ivana Ilić
; Department of Pathology and Cytology, University Hospital Centre Zagreb, Zagreb, Croatia;
Eva Brenner
; University of Zagreb, School of Medicine, Zagreb, Croatia
Luka Bulić
; School of Medicine, University of Zagreb, Zagreb, Croatia;
Mia Lorencin Bulić
; University Hospital Dubrava, Zagreb, Croatia
Abstract
While basal cell carcinoma is the most common type of skin can-
cer in humans, its subepidermal presentation is extremely rare. The risk factors
for basal cell carcinoma development are well-known, but it remains unclear in
which setting the tumor restricts itself to the dermal compartment. We present
the fifth known case of subepidermal basal cell carcinoma. However, this par-
ticular presentation is unique due to arising beneath a capillary malformation.
The patient had previously undergone multiple laser treatments which yielded
no success. Initially, the vascular malformation was removed and sent for histo-
pathological diagnosis. After the discovery of basal cell carcinoma, wide surgical
resection was performed. The patient had no recurrence up to the last follow-up
at 18 months postoperatively. This case demonstrates a new presentation of a
very rare condition, but also highlights the importance of histopathological ex-
amination and the need for future research on any possible association between
laser therapy and carcinogenesis.
Keywords
case report, subepidermal basal cell carcinoma; capillary malfor- mation; laser treatment
Hrčak ID:
316458
URI
Publication date:
15.12.2023.
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