Liječnički vjesnik, Vol. 146 No. 3-4, 2024.
Izvorni znanstveni članak
https://doi.org/10.26800/LV-146-3-4-4
Peripheral arterial disease in hemodialysis patients
Ivica Horvatić
orcid.org/0000-0001-9050-5747
Alen Andrović
orcid.org/0000-0002-1751-2091
Ivana Bedalov Crnković
Ivana Delonga
Sonja Dits
Slava Doko
Ivan Durlen
Željka Grđan
Ivančica Hršak
Dijana Knežević Strinavić
Iva Papac Bebek
Ana Šavuk
orcid.org/0000-0002-6804-9025
Boris Kudumija
Draško Pavlović
orcid.org/0000-0002-2380-869X
Sažetak
Objective: To explore the prevalence of leg ulcers (LU) and non-traumatic lower extremity amputations (LEA) as signs of ischemic peripheral arterial disease (PAD) in patients treated by chronic intermittent hemodialysis (HD) and to examine their correlation with other clinical and laboratory parameters. Patients and methods: Three hundred thirty-nine patients from five HD centers were included in this cross-sectional study conducted between January and May of 2023. Patient clinical history, past documentation and thorough clinical examination (especially peripheral pulsations), as well as last routine laboratory findings were considered. Multivariate logistic regression analysis was used to determine the risk factors for LU and LEA. Results: Two hundred two men (61.4%), 119 diabetic patients (36.2%), with median HD treatment duration of 40 months were included. PAD was found in 98 (27.8%), LU in 42 (12.8%) and LEA in 40 (12.2%) patients. LU patients had more often PAD, diabetes, coronary artery disease, absent or diminished pulsations on all lower extremity locations and hypoalbuminemia
and were more often smokers. LEA patients had more often PAD, diabetes, LU, absent or diminished pulsations on all lower extremity locations and hypoalbuminemia and were younger, taller and more often smokers. In multivariate logistic regression risk factors associated with LU, PAD, diabetes, longer HD duration and hypoalbuminemia
were found. As risk factors for LEA, PAD, LU, diabetes, smoking, younger age and hypoalbuminemia were found. Conclusion: The prevalence of PAD in HD patients is higher compared to the general population, and diabetes, smoking and HD vintage are additional risk factors. Larger, prospective studies, as well as frequent clinical examinations are needed to prevent further morbidity and mortality.
Ključne riječi
PERIPHERAL ARTERIAL DISEASE – complications, epidemiologija, etiologija; FOOT ULCER – epidemiology, etiology; AMPUTATION, SURGICAL – statistics and numerical data; RENAL DIALYSIS – adverse effects; KIDNEY FAILURE, CHRONIC – complications, therapy; DIABETES MELLITUS – epidemiology; RISK FACTORS
Hrčak ID:
317654
URI
Datum izdavanja:
2.6.2024.
Posjeta: 0 *