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Archives of Industrial Hygiene and Toxicology, Vol. 59 No. 4, 2008.

Short communication, Note

https://doi.org/10.2478/10004-1254-59-2008-1918

How Volatile Organic Compounds Affect Free Radical and Antioxidant Enzyme Activity in Textile Workers

Sibel Bayil ; University of Gaziantep, Vocational School of Higher Education for Health Services, Gaziantep, Turkey
Hulya Cicek ; University of Gaziantep, Vocational School of Higher Education for Health Services, Gaziantep, Turkey
Iclal Geyikli Cimenci ; University of Gaziantep, Vocational School of Higher Education for Health Services, Gaziantep, Turkey
Muhsin Hazar ; University of Gaziantep, Vocational School of Higher Education for Health Services, Gaziantep, Turkey

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Abstract

Various effects of exposure to volatile organic compounds (VOC) have recently become an important issue because of their widespread use in industry. The aim of this study was to determine the effect of volatile organic solvents commonly used in textile paint industry on free radical levels and the antioxidant enzyme system in textile workers. The study included twenty exposed workers and twenty controls. Blood samples were taken after an overnight fast of 10 to 12 hours. Malondialdehyde (MDA) and total antioxidant capacity (TAC) were studied in serum while super oxide dismutase (SOD) activity was studied in erythrocytes. Statistical analysis was performed using the ANOVA and Kruskall-Wallis analysis tests. MDA and SOD were significantly higher in textile workers than in controls (p<0.01). In contrast, no significant difference was observed between them for TAC (p>0.05).
Elevated MDA levels in textile workers may indicate increased lipid peroxidation as a result of long-term exposure to organic solvents, whereas elevated SOD activity suggests that the antioxidant system was activated to counter lipid peroxidation. The results suggest that textile workers occupationally exposed to volatile organic solvents make a risk group and require more frequent periodic examinations.

Keywords

occupational exposure; malondialdehyde; total antioxidant capacity; super oxide dismutase; biomonitoring

Hrčak ID:

29561

URI

https://hrcak.srce.hr/29561

Publication date:

8.12.2008.

Article data in other languages: croatian

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