Acta clinica Croatica, Vol. 63. No. 2, 2024.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2024.63.02.1
The effect of uric acid level on the severity of COVID-19
Kubra Aydin Bahat
; Department of Internal Medicine, Division of Nephrology, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey
Sažetak
Epidemiological and clinical features of COVID-19 have been reported, but
risk factors need to be determined to predict the course of the disease. In our study, we aimed to
determine the effect of uric acid level on the severity of the disease. COVID-19 patients who received
inpatient treatment between March 11, 2020 and May 30, 2020, and whose uric acid level was
measured were included in the study. Demographic characteristics, comorbidities, symptoms, clinical
course, laboratory parameters, and treatments were recorded. Th e study included 83 patients, of these
43 (52%) were males. The mean age was 59±17.1 years. The mean uric acid and albumin levels of
the patients who needed oxygen were lower than in those who did not need oxygen (p=0.471 and
p=0.057, respectively). There was a significant relationship between the presence of hypouricemia and
mortality (p=0.019). In addition, the mean uric acid levels of patients who needed intensive care or
died were lower than the mean uric acid levels of patients who did not need intensive care or who lived
(p=0.665 and p=0.241, respectively). Oxygen need, intensive care need, and low uric acid level were
found to be associated with increased length of hospital stay (p=0.00, p=0.001, p=0.012, and r=-0.276,
respectively). Our study results suggest that uric acid levels may be associated with disease severity in
the course of COVID-19.
Ključne riječi
COVID-19; Oxygen support; Prognosis; Uric acid
Hrčak ID:
327110
URI
Datum izdavanja:
31.10.2025.
Posjeta: 1.043 *