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Cardiologia Croatica, Vol. 19 No. 11-12, 2024.

Meeting abstract

https://doi.org/10.15836/ccar2024.606

Percutaneus coronary intervention without stents - our experience with drug-coated balloons

Matija Vrbanić orcid id orcid.org/0000-0002-3229-9436 ; Dubrava University Hospital, Zagreb, Croatia
Ljiljana Švađumović orcid id orcid.org/0000-0002-9068-2716 ; Dubrava University Hospital, Zagreb, Croatia
Biljana Šego orcid id orcid.org/0000-0002-0806-1233 ; Dubrava University Hospital, Zagreb, Croatia
Zoran Marić orcid id orcid.org/0000-0002-9121-4631 ; Dubrava University Hospital, Zagreb, Croatia
Darko Navoj orcid id orcid.org/0000-0001-8899-6524 ; Dubrava University Hospital, Zagreb, Croatia
Kristijana Radić ; Dubrava University Hospital, Zagreb, Croatia
Vlatka Funduk ; Dubrava University Hospital, Zagreb, Croatia
Ivica Benko orcid id orcid.org/0000-0002-1878-0880 ; Dubrava University Hospital, Zagreb, Croatia
Nikola Krajna orcid id orcid.org/0009-0008-7628-6603 ; Dubrava University Hospital, Zagreb, Croatia
Mario Salajec orcid id orcid.org/0009-0002-8406-4142 ; Dubrava University Hospital, Zagreb, Croatia

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Abstract

Keywords

drug-coated balloon; complex lesions; preparation

Hrčak ID:

328891

URI

https://hrcak.srce.hr/328891

Publication date:

13.12.2024.

Visits: 328 *

Copyright statement: Croatian Cardiac Society

Copyright: 2024, Croatian Cardiac Society

Date received: 12 October 2024

Date: 31 October 2024

Publication date: November 2024

Publication date: November 2024

Volume: 19

Issue: 11-12

Page: 606

Publisher ID: CC 2024 19_11-12_606

DOI: 10.15836/ccar2024.606

Article Information (continued)

Categories:

Subject: Extended Abstract

Categories:

Subject: Invasive and interventional cardiology

KEYWORDS: :

KEYWORDS:

Keyword: drug-coated balloon

Keyword: complex lesions

Keyword: preparation

Percutaneus coronary intervention without stents - our experience with drug-coated balloons

[https://orcid.org/0000-0002-3229-9436] Matija Vrbanić[1][*]

[https://orcid.org/0000-0002-9068-2716] Ljiljana Švađumović[1]

[https://orcid.org/0000-0002-0806-1233] Biljana Šego[1]

[https://orcid.org/0000-0002-9121-4631] Zoran Marić[1]

[https://orcid.org/0000-0001-8899-6524] Darko Navoj[1]

[https://orcid.org/0000-0002-6098-254X] Kristijana Radić[1]

[https://orcid.org/0000-0001-7070-188X] Vlatka Funduk[1]

[https://orcid.org/0000-0002-1878-0880] Ivica Benko[1][2]

[https://orcid.org/0009-0008-7628-6603] Nikola Krajna[1]

[https://orcid.org/0009-0002-8406-4142] Mario Salajec[1]

 

[1] Dubrava University Hospital, Zagreb, Croatia

[2] University of Applied Health Studies, Zagreb, Croatia

Author notes:

Correspondence to: [*] ADDRESS FOR CORRESPONDENCE: Matija Vrbanić, Klinička bolnica Dubrava, Avenija Gojka Šuška 6, HR-10 000 Zagreb, Croatia. / Phone: +385-91-2112-007 / E-mail: mvrbanic@kbd.hr

Invasive and interventional cardiology has significantly advanced with the emergence of innovative technologies aimed at improving patient outcomes. One such advancement is the use of drug-coated balloons (DCBs), which integrate balloon angioplasty with localized pharmacological therapy. These balloons play a crucial role in the treatment of coronary artery disease, particularly in complex lesions and in patients at high risk of restenosis. Preparation of lesions prior to intervention is fundamental for optimizing results. The characteristics of lesions, including morphology and the degree and type of calcification in the coronary artery, significantly influence the choice of treatment strategy. The specificity of treatment with this method is localized drug delivery, which minimizes systemic side effects and maximizes drug concentration at the target area, contributing to better outcomes. The efficacy of DCBs is not solely based on immediate procedural success but also on long-term results. Studies show that patients treated with DCBs have improved clinical outcomes, including reduced rates of restenosis. Furthermore, the incorporation of drug delivery technology via balloons into clinical practice requires a comprehensive understanding of the optimal pharmacological agents used in conjunction with DCBs. Immunomodulatory agents, including sirolimus and paclitaxel, have been utilized with demonstrated effectiveness in reducing restenosis rates. The selection of appropriate pharmacological agents is crucial for achieving the desired therapeutic outcomes and should be tailored to individual patient needs. (1) The use of drug-coated balloons represents a significant advancement in the field of interventional cardiology. As clinical experience with DCBs continues to grow, they are likely to become an integral part of strategies aimed at improving long-term outcomes in patients with coronary artery disease.

LITERATURE

1 

Jeger RV, Eccleshall S, Wan Ahmad WA, Ge J, Poerner TC, Shin ES, et al. International DCB Consensus Group. Drug-Coated Balloons for Coronary Artery Disease: Third Report of the International DCB Consensus Group. JACC Cardiovasc Interv. 2020 June 22;13(12):1391–402. https://doi.org/10.1016/j.jcin.2020.02.043 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/32473887

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