Pregledni rad
https://doi.org/10.3325/cmj.2023.64.123
Hematopoietic stem cell transplantation in Zagreb: the first 40 years
Boris Labar
; Professor Emeritus, University of Zagreb School of Medicine, Zagreb, Croatia
*
* Dopisni autor.
Sažetak
Hematopoietic stem cell transplantation is the most effective treatment for acute leukemia, severe aplastic anemia,
and some hereditary hematological disorders. The principal source of stem cells in this procedure are bone marrow
and peripheral blood cells. In recent years, the transplantation outcome has significantly improved. The availability
of the donor no longer poses a problem, as transplantation has been performed routinely from related, unrelated,
and haploidentical donors. A high success rate has been
reported in elderly patients transplanted with reduced-intensity conditioning. Improved patient care has decreased
toxicity and mortality after treatment. This article gives an
overview of the 40-year history of the Zagreb transplant
program. It also discusses the use of hematopoietic stem
cell transplantation in various hematological disorders,
with a special emphasis on the publications by the Zagreb
transplant team
Ključne riječi
Hrčak ID:
331521
URI
Datum izdavanja:
31.5.2023.
Posjeta: 413 *