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https://doi.org/10.3325/cmj.2024.65.13

The utility of the systemic immune inflammation and systemic inflammation response indices in suspected intermediate-risk pulmonary embolism

Muhammed Fuad Uslu ; Department of Internal Medicine, Elazig Fethi Sekin City Hospital, Elazig, Turkey *
Mustafa Yilmaz ; Department of Emergency Medicine, Firat University of Medicine, Elazig, Turkey
Metin Ateşçelik ; Department of Emergency Medicine, Firat University of Medicine, Elazig, Turkey
Feti Ahmet Atilgan ; Department of Emergency Medicine, Elazig Fethi Sekin City Hospital, Elazig, Turkey

* Dopisni autor.


Puni tekst: engleski pdf 260 Kb

str. 13-19

preuzimanja: 55

citiraj


Sažetak

Aim To evaluate the utility of the systemic immune inflammation index (SII) and systemic inflammation response index (SIRI) in diagnosing pulmonary embolism (PE) in emergency medicine.
Methods We retrospectively reviewed the data of patients
who presented to the emergency department and underwent contrast-enhanced computed tomography pulmonary angiography for suspected PE between January 1 and
December 31, 2021. In 81/168 patients, the diagnosis of
PE was confirmed and in 87/168 it was rejected. The data
were analyzed with receiver operating characteristic analysis and binary logistic regression analysis.
Results Patients with PE had a higher white blood cell
count (P<0.001), neutrophils (P=0.002), monocytes
(P=0.013), neutrophil/lymphocyte ratio (P<0.001), SII
(P<0.001), and SIRI (P<0.001), and a lower lymphocyte
count (P=0.002). The SII had a sensitivity of 75.31% and
a specificity of 71.26%, while the SIRI had a sensitivity of
82.72% and a specificity of 68.97%. Binary logistic regression analysis showed that the Wells score, D-dimer level,
and SII independently influenced the diagnosis of PE.
Conclusion The SII and SIRI may be used to support the
diagnosis of PE in the emergency department.

Ključne riječi

Hrčak ID:

331894

URI

https://hrcak.srce.hr/331894

Datum izdavanja:

22.2.2024.

Posjeta: 132 *