Review article

Contribution of insulin to mood disorders

Ivan Đuran ; School of Medicine, University of Zagreb, Zagreb, Croatia

Abstract

Insulin is one of the most important hormones in the human body. Research on insulin has moved from it being an anabolic hormone controlling blood glucose levels, to a hormone that has many different effects not only on the internal organs and the musculoskeletal system but also profound effects on the central nervous system (CNS). The aim of this literature review is to serve as an aid, or a starting point, in understanding the influence of insulin on the CNS, as it will provide valuable insight into various molecular interplays and interesting pathways by which insulin could possibly modify not only mood, but the whole understanding of mood disorder patophysiology.

Keywords

central nervous system; dopamine; insulin resistance; molecular psychiatry; mood disorders; serotonin

Hrčak ID:

353430

URI

https://hrcak.srce.hr/353430

Publication date:

20.12.2024.

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