Paediatria Croatica, Vol. 53 No. 1, 2009.
Stručni rad
HAEMOPHILIA IN THE PAEDIATRIC DEPARTMENT, KBC SPLIT: PREVENTION OF BLEEDING
Srđana Čulić
orcid.org/0000-0002-7317-6475
; KBC Split
Lena Ozretić
Dubravka Kuljiš
Višnja Armanda
Sažetak
Haemophilia is a genetic haemorrhagic disorder characterised by the absence of VIII or IX coagulation factors and is treated with supplemental factors VIII or IX. Haemophilia A is the most common and accounts for 70% of all inherited coagulopathies. At the Paediatric Department, KBC Split from 01.01. 2003 to 15.02.2008 28 haemophiliacs were registered, 21 with haemophilia A (75%), and 7 with haemophilia B (25%). 8 (38%) patients had mild haemophilia A , moderate 6 (29%), and severe 7 (33%). 2 children (29%) had moderate haemophilia B, and severe 5 (71%). 12 (42%) patients received monthly prophylaxis , 6 with severe haemophilia A (67%), and 3 (33%) with severe haemophilia B. Children were treated in the outpatients' clinic for 649 days, on average 6 days, most often because of an ankle, elbow, or epistaxis and knee injury. Children were hospitalized 17 times, 79% with haemophilia A, and 21% with haemophilia B, mostly because of head, frontal thoracic and joint injuries. Hospitalisation lasted on average 8 days. Inhibitors were not registered, while two children developed mild haemophilic arthropathy.
Ključne riječi
Descriptors: HEMOPHILIA A – complications, drug therapy; HEMOPHILIA B – complications, drug therapy; HEMARTHROSIS – prevention and control; BLOOD COAGULATION FACTORS – therapeutic use, administration and dosage
Hrčak ID:
41161
URI
Datum izdavanja:
3.7.2009.
Posjeta: 1.972 *