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BIPOLAR DISORDER AND METABOLIC SYNDROME: COMORBIDITY OR SIDE EFFECTS OF TREATMENT OF BIPOLAR DISORDER

Dragan Babić ; School of Medicine, University of Mostar, Bosnia and Herzegovina
Boris Maslov ; School of Medicine, University of Mostar, Bosnia and Herzegovina
Katica Nikolić ; School of Medicine, University of Mostar, Bosnia and Herzegovina
Marko Martinac ; School of Medicine, University of Mostar, Bosnia and Herzegovina
Suzana Uzun ; University Department, Vrapče Psychiatric Hospital, Bolnička cesta 32, 10090 Zagreb, Croatia
Oliver Kozumplik ; University Department, Vrapče Psychiatric Hospital, Bolnička cesta 32, 10090 Zagreb, Croatia

Sažetak

Objective: There is evidence that people with mental disorders are more likely to suffer from metabolic syndrome. In the last decades there has been an increase in interest for researching metabolic syndrome in psychiatric patients and plenty of evidence about their association. However, investigations on the prevalence of metabolic syndrome in patients with bipolar disorder are still surprisingly rare. The aim of this paper is to analyze comorbidity of bipolar disorder and metabolic syndrome, and the association of treatment with antipsychotics and mood stabilizers with metabolic syndrome, as well as to point out the necessity of appropriate preventive measures and treatment of metabolic syndrome in patient with bipolar disorder.
Content analysis of literature: Literature research included structured searches of Medline and other publications on the subject
of comorbidity of bipolar disorder and metabolic syndrome, and the association of treatment with antipsychotics and mood stabilizers with metabolic syndrome, as well as preventive measures and treatment of metabolic syndrome in patient with bipolar disorder.
Conclusion: Metabolic syndrome is present in 8-56% of patients suffering from bipolar disorder. Metabolic syndrome in patients
with bipolar disorder can significantly contribute to morbidity and mortality, and it is certainly necessary to think of it, to take
adequate preventive and therapeutic measures in treating its individual components. Further investigation on association between
bipolar disorder and metabolic disorder, and the association of treatment with antipsychotics and mood stabilizers with metabolic
syndrome are necessary.

Ključne riječi

metabolic syndrome; bipolar disorders; prevalence-side effects- comorbidity

Hrčak ID:

48621

URI

https://hrcak.srce.hr/48621

Datum izdavanja:

10.2.2010.

Posjeta: 2.028 *